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Clinical Studies

These studies where done using much higher doses of their respective ingredients (Pyruvate, Citosan, and Fenugreek). Slim Again Plus uses all of these ingredients at lower doses and has yet to do a clinical study in its current form.

Want more proof?

Select ingredients found in Slim Again Plus are backed by a pedigree of impressive scientific research. Many of the scientific articles listed below have been published in highly regarded peer reviewed medical journals.

Note: References to medical journals, research reports, medical doctors and individuals do not constitute an endorsement of Power2Fitness products. The scientific research below was done with significantly larger quantities of ingredients than are contained in Slim Again Plus. Results are not typical. Individual results may vary. These statements have not been evaluated by the Food and Drug Administration. Power2Fitness products are not intended to diagnose, prevent, treat or cure disease.

Weight Loss | Fat Loss | Fat Binding | Endurance | Blood Sugar Metabolism | Cholesterol | References 

Weight Loss

Clinical studies conducted by medical doctors revealed that subjects ingesting pyruvate (a primary ingredient in Slim Again Plus) experienced an average greater weight loss and greater fat loss when compared to the placebo study group.

-American Journal of Clinical Nutrition
Ronald T. Stanko, M.D., et al.
Univ. of Pittsburgh School of Medicine



Medical doctors found that subjects consuming 2000 calories daily along with low-doses of pyruvate (a primary ingredient in Slim Again Plus) lost 4.8 pounds of body fat in six weeks.

-Current Therapeutic Research
Carlon Colker, M.D., et al.
Beth Israel Medical Center



Fenugreek (a primary ingredient in Slim Again Plus) may promote weight loss because it slows the rate of gastric emptying, so they will feel full longer and their appetite may be suppressed.

-Nutrition Research (Journal)
Dr. R.D. Sharma, et., al.
Human Clinical Study



The Helsinki Study was a randomized, double blind placebo controlled study performed in human subjects. Chitosan (a primary ingredient in Slim Again Plus) was associated with significant greater weight loss than the placebo group.

-Human Weight Loss Study
Helsinki vivo Study
Laboratory environment
 

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Fat Loss

Clinical studies conducted by medical doctors revealed that subjects ingesting pyruvate (a primary ingredient in Slim Again Plus) experienced greater weight loss and fat loss when compared to the placebo study group.

-American Journal of Clinical Nutrition
Ronald T. Stanko, M.D., et al.
Univ. of Pittsburgh School of Medicine



Medical doctors found that subjects consuming 2000 calories daily along with low-doses of pyruvate (a primary ingredient in Slim Again Plus) lost 4.8 pounds of body fat in six weeks.

-Current Therapeutic Research
Carlon Colker, M.D., et al.
Beth Israel Medical Center


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Fat Binding

Results revealed significant decreases were reported in LDL cholesterol for subjects consuming Chitosan Plus (a primary ingredient in Slim Again Plus) compared to the placebo. In addition the significant reduction in plasma carotenoids indicates a marked decrease in fat absorption.

-Human Fat-Binding Pilot Study
East Tennessee State University
Johnson City Medical Center



Having tested the fat-binding properties of Chitosan (a primary ingredient in Slim Again Plus) against various other fat-binding products, the results showed that Chitosan binds more fat than similar raw ingredients or other finished products tested.

-Research Pilot Study
Susie W. Rockway, PhD., CNS
St. Luke's Medical Center 


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Endurance

Researchers found that supplementation with pyruvate (a primary ingredient in Slim Again Plus) significantly increased muscular endurance in both the arms and legs.

-Journal of Applied Physiology
Ronald T. Stanko, M.D., et al.
Univ. of Pittsburgh School of Medicine 


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Blood Sugar Metabolism

Human clinical studies confirmed that consumption of fenugreek (ingredient in Slim Again Plus) may help promote blood sugar balance, mostly by decreasing the glycemic index of food consumed, which improves blood sugar response.

-Nutrition Research (Journal)
Dr. R.D. Sharma, et., al.
Human Clinical Study


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Cholesterol

Results revealed significant decreases were reported in LDL cholesterol for subjects consuming Chitosan Plus (a primary ingredient in Slim Again Plus) compared to the placebo. In addition the significant reduction in plasma carotenoids indicates a marked decrease in fat absorption.

-Human Fat-Binding Pilot Study
East Tennessee State University
Johnson City Medical Center



Ingestion of (25 grams) of fenugreek (ingredient in Slim Again Plus) seed powder resulted in a significant reduction of total cholesterol, LDL and VLDL cholesterol and triglyceride levels, which indicates the beneficial effects of fenugreek seeds in diabetic subjects.

-Phytotherapy Research (Journal)
Dr. R.D. Sharma, et., al.
Dept of Medicine, SN. Medical College 


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Please refer to "Clinical Study Medical References" for specific details regarding the medical research referenced above. References to medical journals, research reports, medical doctors and individuals do not constitute an endorsement of Power2Fitness products. Results not typical. Individual results may vary.

These statements have not been evaluated by the Food and Drug Administration. Power2Fitness products are not intended to diagnose, prevent, treat or cure disease.


Clinical Study References and Medical Research

1. Stanko RT, Tietze DL, Arch JE. Body composition, energy utilization, and nitrogen metabolism with a 4.25-MJ/d low-energy diet supplemented with pyruvate. American Journal of Clinical Nutrition 1992;56:630–5.
2.Stanko RT, Inhibition of regain in body fat with addition of 3-carbon compounds to the diet refeeding after weight reduction. International Journal of Obesity (19960 20,925-930 3. Kalman D, Colker CM, Wilets I, et al. The effects of pyruvate supplementation on body composition in overweight individuals. Nutrition 1999;15:337–40.
4. Kalman D, Colker CM, Stark S, et al. Effect of pyruvate supplementation on body composition and mood. Current Therapeutic Research 1998;59:793–802.
5. Stanko RT, Robertson RJ, Galbreath RW, et al. Enhanced leg exercise endurance with a high-carbohydrate diet and dihyroxyacetone and pyruvate. Journal of Applied Physiology 1990;69:1651–6.
6. Stanko RT, Robertson RJ, Spina RJ, et al. Enhancement of arm exercise endurance capacity with dihydroxyacetone and pyruvate. Journal of Applied Physiology 1990;68:119–24.
7. Robertson, R.J., Stanko,R.T. Goss, F.L., Spina, R.J., Reilly, J.J., Greenwalt, K.D. Blood glucose extraction as a mediator of perceived exertion during prolonged exercise. European Journal of Applied Physiology 61:100-105, 1990.
8. Stanko RT, Tietze DL, Arch JE. Body composition, energy utilization, and niytogen metabolism with a severly restricted diet supplemented with dihydroxyacetone and pyruvate. American Journal of Clinical Nutrition 1992; 55: 771-776.
9. Colker CM, Kalman D, Antonio J. Effects of Low Dose Pyruvate on Biochemical Markers and Lipid Levels in Overweight Individuals. Journal of the American College of Nutrition 1998 Volume 17
10. Colker CM, Antonio J, Kalman D. Effects of Pyruvate on Body Composition and Lipid Levels of Overweight Individuals. Journal of American Dietetics Association 1998 Annual Conferenc
11. AI-Habori A. and Raman, A. "Antidiabetic and Hypocholesterolaemic Effects of Fenugreek." Phytotherapy Research. 12:233-42, 1998.
12. Madar Z, Abel R, Samish S and Arad J. "Glucose-Lowering Effect of Fenugreek in Non-Insulin Dependent Diabetics." Eur J Clin Nutr. 42:51-54, 1988.
13. Sharma RD. "Effect of Fenugreek Seeds and Leaves on Blood Glucose and Serum Insulin Responses in Human Subjects." Nutrition Research. 6:1353-64, 1986.
14.Sharma RD, Raghuram TC, and Sudhakar Rao N. "Effect of Fenugreek Seeds on Blood Glucose and Serum Lipids in Type I Diagetes." Eur J Clin Nutr. 44:301-06, 1990.
15. Sharma RD, Raghuram RC. "Hypoglycaemic Effect of Fenugreek Seeds in Non-Insulin Dependent Diabetic Subjects." Nutrition Research. 10:731-739, 1990.
16. Sharma RD, et al. "Hypolipidaemic Effect of Fenugreek Seeds: a Chronic Study in Non-insulin Dependent Diabetic Patients." Phytotherapy Research. 10:332-34, 1996.
17. Sowmya, R and Rajyalakshmi P. "Hypocholesterolemic Effect of Germinated Fenugreek Seeds in Human Subjects." Plant Foods for Human Nutrition. 53:359-65, 1999.
18. Sharma RD, et al. "Toxicological Evaluation of Fenugreek Seeds: a Long-Term Feeding Experiment in Diabetic Patients." Phytotherapy Research. 10:519-20, 1996.
19. Udayasekhara Rao P, et al. "Short Term Nutritional and Safety Evaluation of Fenugreek." Nutrition Research. 16:1495-1505, 1996.
20. Garti N, et al. "Fenugreek Galactomannans as Food Emulsifiers." Lebensmittel-Wissenschaft and und Technologie, Aug. 1997.
21. Rockway SW. Chitosan Fat-Binding Report PharmaNutrients 1-8, 9/18/00
22. Heldman E, Gudmundsson S, Lilja B, Wadstein J. Effects of Chitosan L112 on Animal Fat Resorption in Human. Report: Malmo University Hospital 7;8-23, 1997

These studies where done using much higher doses of their respective ingredients (Pyruvate, Citosan, and Fenugreek). Slim Again Plus uses all of these ingredients at lower doses and has yet to do a clinical study in its current form
 

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